By: Mark Lange, PhD
Ulcerative colitis (UC) is an inflammatory disorder which affects the entire colorectum and is one of the two major forms of inflammatory bowel diseases along with Crohn’s disease. It is one of the most difficult gastrointestinal diseases to manage. UC has been closely tied with inflammatory pathways.
Curcumin is a safe botanical and, given its well-established anti-inflammatory properties, may be an effective treatment for managing and/or treating UC and subsequently improving the overall quality of life. In this study, curcumin combined with turmeric essential oil was reportedly significantly more powerful than curcumin alone in attenuating the disease activity in an experimental mouse model of colitis.
The study used BCM-95 curcumin, which is a patented complex of curcumin and essential turmeric oils. Although BCM-95 is better absorbed than plain curcumin, its beneficial activities are not solely the result of absorption, but rather the anti-inflammatory synergism of both compounds.
Source: Nature Scientific Reports published online 11 April 2017. DOI:10.1038/s41598-017-00812-6