By: Mark Lange, PhD
Vitamin D deficiency may be a contributor to rigid artery walls – a predictor of cardiovascular disease. A four-month study of 70 African-Americans ages 13-45 – all with some degree of arterial stiffness – took 4000 IU of vitamin D3 daily. Arterial stiffness improved with vitamin D supplementation in a dose-response manner within this population. Participants saw a 10.4 percent reduction in arterial stiffness. Participants taking 2000 IU vitamin D3 daily had a 2 percent reduction.
Heart disease is the leading cause of death in the United States. African-Americans have higher rates than other populations and the disease tends to occur earlier in life. The authors write that arterial stiffness and vitamin D deficiency might be potential contributors.
More than 80% of American have vitamin D insufficiency or deficiency.
Source: Anas Raed, et al. Dose responses of vitamin D3 supplementation on arterial stiffness in overweight African Americans with vitamin D deficiency: A placebo controlled randomized trial. PLOS ONE 2017; 12 (12)